Guangdong Province Natural Science Foundation of China2016A030313500,2016A030310253;Special Foundation of Science and Technology Development of Science and Technology Department of Guangdong Province in 2016 Special Foundation for Public Welfare Research and Capacity Building 2016A020215007广东省自然科学基金2016A030313500、2016A030310253;2016年广东省科学技术厅科技发展专项资金公益研究与能力建设方向2016A020215007