Cutaneous Radiation-Associated Angiosarcoma After Cervical Cancer Treatment: A Case Report
Introduction::Cutaneous radiation-associated (cRAA) angiosarcoma is a rare malignant neoplasm derived from vascular endothelial cells, but a relatively commonly recognized complication of radiation therapy.Here, we present a patient with cRAA, who undergone radiochemotherapy for cervical cancer 11 years ago.Case presentation::A 48-year-old woman presented with a 6-month history of painless purple skin plaques and nodules on her lower abdomen and right thigh. The patient had undergone radiochemotherapy for cervical cancer 11 years ago. A skin biopsy showed a diffuse proliferation of irregular anastomosing dilated vascular structures with atypical endothelial cells. She was diagnosed as cRAA according to clinical and histological manifestations.Discussion::cRAA is a rare malignant neoplasm but it is a complication of radiation therapy. The incidence of cRAA has increased in recent years. Clinical and pathological manifestations are highly varied. Radical resection is the preferred treatment.Conclusion::Patients with suspicious violaceous lesions should undergo biopsy. Clinical suspicion and pathological examination are of the utmost importance for cRAA.
cutaneous angiosarcoma、radiation therapy
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This work was supported by the CAMS Innovation Fund for Medical SciencesNo. CIFMS-2017-I2M-1-017;the PUMC Youth FundNo. 3332017168
2023-05-30（万方平台首次上网日期，不代表论文的发表时间）
共3页
263-265
