Reactive perforating collagenosis

摘要：

HistopathologyHistological features of reactive perforating collagenosis (RPC) vary according to stage of disease.The pathological manifestations of lesions that did not form an umbilical fossa in the early stages,degenerate collagen fibers accumulate in dermal papillae and epidermal hyperplasia may be seen.The upper epidermis is atrophied,and a thin layer of keratinized material is visible in the center.Typical acanthosis is visible on both sides of the lesion.In the late stage,epidermis cup-shaped depression can be seen in the epidermis,and it filled with columnar overlying keratin plug that consists of parakeratotic debris,denatured collagen fibers and inflammatory cells”1”.The epidermis below is obviously thin.It is locally visible that degenerative collagen fibers pass through the epidermi vertically.The epidermis on both sides of the cup-shaped structure show acanthosis and hyperkeratosis,and infiltration of lymphoid cells is observed in the superficial dermis and around the blood vessels (Figure 1).Blue-stained collagen fibers are visible in the superficial dermis and epidermis inMasson staining.

所属期刊栏目：2

在线出版日期：2019-05-10（万方平台首次上网日期，不代表论文的发表时间）

页数：共3页

页码：62-64