10.3760/cma.j.issn.2096-5540.2018.04.004
Advances in postoperative radiotherapy for keloids
IntroductionKeloids, a type of skin lesion that presents as patho-logically excessive dermal fibrosis and aberrant wound healing, are caused by cell proliferation and hyaline degeneration of connective tissues. The specific pathogenesis of keloids is still unknown”1-2”. There are multiple therapeutic strategies for keloids, including surgery, cryotherapy, laser or light-based therapy, and intralesional corticosteroid injection. However, none of these is optimal. Surgical excision combined with adjuvant radiation is considered to be a safer and more efficacious method”3”. From publicly available data, the recurrence rate of keloids after simple surgical excision amounts to 45%-100%”4”. Based on published reports, postoperative radiotherapy results in a control rate of 67%- 81%, and the recurrence rate decreases to 24.5%-35%”4-12”. This article reviews papers related to postoperative radiotherapy treatment for keloids, and also discusses radiation types, parameters, safety and effectiveness.
1
the National Natural Science Foundation of China81872545 and 81703152;the CAMS Innovation Fund for Medical SciencesCIFMS-2017-I2M-1-017
2019-01-09(万方平台首次上网日期,不代表论文的发表时间)
共5页
212-216