10.3760/cma.j.issn.2096-5540.2018.03.003
Targeted treatments of psoriasis vulgaris recommended by guidelines
Introduction Psoriasis is a common chronic recurrent inflammatory skin disease with most common clinical form of chronic plaque type (90%).For moderate-to-severe psoriasis vulgaris patients,who were inadequately responding to other synthetic therapies,targeting therapeutic drugs may have unexpected effects.And with the deepening understanding of pathogenesis,the targeted therapy for psoriasis is increasingly diverse and accurate.Biologic agents can block T cell activation,antagonise T cell secretion of tumor necrosis factor alpha (TNF-α),interleukin (IL)-17,IL-23,and other cytokines,and then effectively block the immune inflammatory response.
1
CAMS Innovation Fund for Medical Sciences2016-I2M-1-002;the National Natural Science Foundation of China81472872
2018-10-29(万方平台首次上网日期,不代表论文的发表时间)
共10页
141-150