科技部科研院所开发专项2014EG150134;天津市科技支撑项目14ZCZDSY00001;协和青年科研基金资助,中央高校基本科研业务费专项资金资助2017310027Technology and Development and Research Projects for Research Institutes,Ministry of Science and Technology2014EG150134;Science and Technology Support Plan Project of Tianjin14ZCZDSY00001;PUMC Youth Fund and the Fundamental Research Funds for the Central Universities2017310027