The 2OGD Superfamily:Emerging Functions in Plant Epigenetics and Hormone Metabolism
The 2-oxoglutarate and Fe(Ⅱ)-dependent dioxygenase (2OGD)superfamily includes oxidative enzymes with an active site containing two histidines and (in most cases) one aspartic or glutamic acid residue.This conserved motif is termed the 2-His-1-carboxylate facial triad,chelates iron,and is housed within a double-stranded β-helix fold,also known as the DSBH,jelly-roll,cupin,or Jumonji C fold (Martinez and Hausinger,2015).The reactions catalyzed by 2OGDs (also called 2ODDs,2ODOs,and 2OGXs) include but are not limited to demethylation,demethylenation,hydroxylation,halogenation,desaturation,ring cleavage,ring closure,and epimerization (Farrow and Facchini,2014).
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grants from the Ministerio de Economia,Industria y Competitividad of SpainBIO2014-53063-P;the Generalitat Valenciana PROMETEOII/2014/006 to J.L.M
2019-01-25（万方平台首次上网日期，不代表论文的发表时间）
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1222-1224
