Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis

摘要：

Dear Editor,
Stem cell therapy holds enormous and revolutionary promise to treat various age-related diseases,such as diabetes,heart failure,and Parkinson's disease.However,low retention and survival rate of delivered stem cells,partially due to immuno-logical rejection,constitute major hurdles for the clinical implementation of stem cell therapy(Lei et al.,2021a).Since mounting evidence showed that several types of stem cells mainly exert their therapeutic effects through the secretion of paracrine effects,exosomes,which are released by stem cells and execute most paracrine functions,have begun to draw attention in the field(Tran and Damaser,2015).

机标关键词：exosomes、senescence、stem、cells、from、alleviate、antler、mesenchymal、osteoarthritis

所属期刊栏目：13

分类号：R730.2;G434;R392.1

在线出版日期：2022-05-19（万方平台首次上网日期，不代表论文的发表时间）

页数：共7页

页码：220-226