Systematic biomedical research of the NASA Twins Study facilitates the hazard risk assessment of long-term spaceflight missions
With the extension of the deep space exploration program,the boundaries of human exploration will be pushed forward to the surface of Mars.Over the past nearly 60 years manned spaceflight and experimental findings demonstrated that spaceflight induced bone loss,muscle atrophy,cardiovascular remodeling and space-related medical problems (Durante and Cucinotta,2008).There are some long-term spaceflight missions planned to implement in the next decades,however,health risks and protections from spaceflight exposures are incompletely clear and still remain a primary concern for manned deep space explorations (Zhao et al.,2018;Wang et al.,2019).Although more than 560 people have the spaceflight experience,only four individuals have participated in long-term spaceflight missions lasting 1 year or more (Stepanek et al.,2019).There is an urgent need to better understand the hazards of long-term spaceflight environment,including weightlessness,ionizing radiation,confinement,disrupted circadian rhythm etc.
risk assessment、deep space exploration、circadian rhythm、bone loss
10
V44;R97
We are grateful to Professor Henggui Zhang Manchester University for critical reading and polishing the manuscript.This work was supported by the National Natural Science Foundation of ChinaGrant .81801872 and 31600683;Advanced Space Medico-Engineering Research Project of China 020103.The authors declare that they have no conflict of interest
2019-12-30（万方平台首次上网日期，不代表论文的发表时间）
共3页
628-630
