PML-RARA mutations confer varying arsenic trioxide resistance

摘要：

Dear Editor,Acute promyelocytic leukemia (APL) caused by the malignant proliferation of bone marrow-derived cells,which is driven by the chromosomal translocation,leading to the fusion of the promyelocytic leukemia gene (PML) and the retinoic acid receptor-a gene (RARA) (de The et al.,1990;Goto et al.,2011).

机标关键词：chromosomal translocation、retinoic acid

所属期刊栏目：8

分类号：R73;R56

资助基金：the National Natural Science Foundation of ChinaGrant .31470754 and 31670786;the National High Technology and Development Program of China2016YFC1302400;Doctoral Fund of Ministry of Education of China20130001130003

在线出版日期：2017-05-19（万方平台首次上网日期，不代表论文的发表时间）

页数：共6页

页码：296-301