47. INHIBITORY EFFECT OF LITHIUM CARBONATE ON GENETIC AND OXDATIVE DAMAGE IN CANCER PATIENTS WITH RADIOTHERAPY AND CHEMOTHERAPY

摘要：

Objective: To observe the inhibitory effect of Lithium carbonate (Li2co3) on genetic and oxidative damage in cancer patients. Methods: The single cell gel electrophoresis assay(SCGE)、Micronucleus frequencies tests were used to measure DNA、chromosomal damage. At the same time, the activity of SOD、GSH-Px and the content of-SH、MDA were detected with biochemical tests. Results: For cancer patients, with the increase of taking Li2co3 course, the genetic damage degree of peripheral blood cell relieved gradually, the activity and content of anti-oxidation material and WBC increased significantly. Conclusion: Li2co3 can inhibit genetic da-mage, increase the ability of anti-oxidation and make the myellogenic inhibition relieve.

关键词：Li2co3、cancer patients、genetic damage、oxidation damage

所属期刊栏目：13

分类号：R73(肿瘤学)

在线出版日期：2004-03-26（万方平台首次上网日期，不代表论文的发表时间）

页数：共1页

页码：237