44. Study the level of DNA breakage in workers exposed to styrene by single cell gel electrophoresis

摘要：

Objective: Study the level of DNA breakage in workers exposed to styrene. Methods: 35 workers aging from 18 to 40 exposed to styrene half a year above were observed as exposed group, in the mean time, 57 workers in the same district who hadn”t been exposed to known genotoxicant were selected as control. Bloods of them were sampled and DNA lesions were detected by single cell gel electrophoresis. Results: Compared with control, the ratio between the length of Comet tail and the total length of Comet in exposed group significantly increased, especially it raised following the styrene concentration exposed, but it was not different among different working age groups. Conclusions: DNA is damaged by styrene, and it appears as dose-response relationship.

关键词：Styrene、Single cell gel electrophoresis、DNA lesion

所属期刊栏目：13

分类号：R73(肿瘤学)

在线出版日期：2004-03-26（万方平台首次上网日期，不代表论文的发表时间）

页数：共1页

页码：235-236